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CATHEPSIN D EVALUATION
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| Fresh, frozen, paraffin-embedded, or buffered formalin fixed tissue.
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| Favorable indicator = < 20% of malignant cells
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| The immunohistochemical detection of granular cytoplasmic staining for Cathepsin D is an adverse prognostic indicator for breast carcinoma, especially among node-negative patients. Staining may be helpful in identifying a subset of breast cancer patients that would benefit from adjuvant therapy
This assay uses a commercial kit or one (or more) reagent(s) designated as "research use only" or "investigational use only" by the manufacturer. Test reliability has been validated by in-house evaluation.
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| ICD-9 (Dx) CODE INFORMATION |
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